Artikel XI

1. This Agreement shall be open for signature by the States which have drawn it up.
2. This Agreement shall be subject to ratification, acceptance or approval. The appropriate instruments shall be deposited with the Government of Switzerland.
3. Any State not a signatory to this Agreement may accede on condition that it satisfies the provisions of Article III, paragraph 2. The instruments of accession shall be deposited with the Government of Switzerland.
4. (a) This Agreement shall come into force when ratified, accepted or approved by the majority of States which have drawn it up, and on condition that the total contributions of these States represent at least 70 % of the total of contributions shown in the scale annexed to this Agreement.
(b) For any other signatory or acceding State the Agreement shall come into force on the date of deposit of its instrument of ratification, acceptance, approval or accession.
(c) This Agreement shall initially remain in force for a period of five years. Not less than one year before the close of that period the Conference shall meet for the purpose of deciding by a two-thirds majority of all the Members either to prolong the Agreement without change, or to amend it, or to discontinue European collaboration in the field of molecular biology within the framework of the Agreement.
5. After this Agreement has been in force for five years, a State party to the Agreement may denounce it by giving notification to that effect to the Government of Switzerland. Such denunciation shall take effect:
(a) at the end of the current financial year if the notification has been given during the first nine months of that financial year;
(b) at the end of the next financial year, if the notification has been given in the last three months of the current financial year.
6. If a Member fails to fulfil its obligations under this Agreement, it may be deprived of its membership by decision of the Conference taken by a majority of two-thirds of all the Members. Such decision shall be notified to signatory and acceding States by the Secretary-General.
7. The Government of Switzerland shall notify signatory and acceding States of:
(a) all signatures;
(b) the deposit of any instrument of ratification, acceptance, approval or accession;
(c) the entry into force of this Agreement;
(d) all written acceptances notified under Article IX, paragraph 3;
(e) the entry into force of any amendment; and
(f) any denunciation signified in accordance with Article XI, paragraph 5.
8. The Government of Switzerland shall, upon the coming into force of this Agreement, register it with the Secretary-General of the United Nations in accordance with Article 102 of the Charter of the United Nations.